Equine
Core Vaccines Every Horse Needs

There are many possible dreadful diseases that horses can contract through various insect vectors, ticks, wildlife and even wounds that are rather easy to prevent with routine core vaccinations. Oklahoma has just about every insect known to man to offer, as all Oklahomans are fully aware of especially in the spring and summer, making it a very good environment for some of these key viruses to spread. The five types of diseases that will be discussed in this article are commonly referred to as the deadly five, and that is why they make the core vaccine list because if one of these diseases is contracted it can be game over for your horse. Before spring arrives, the core vaccines should be on every horse owners to do list as a common health care checklist that should be just as routine as deworming and dental care.
The American Association of Equine Practitioners (AAEP) and American Veterinary Medical Association (AVMA) have established key guidelines for vaccinations for horses that are required based on risk to the public and to the horse themselves. The five diseases listed as core vaccines are Rabies, Tetanus, Eastern equine encephalomyelitis virus, Western equine encephalomyelitis virus and West Nile virus.
The AVMA defines core vaccinations as those “that protect from diseases that are endemic to a region, those with potential public health significance, required by law, virulent/highly infectious, and/or those posing a risk of severe disease. Core vaccines have clearly demonstrated efficacy and safety, and thus exhibit a high enough level of patient benefit and low enough level of risk to justify their use in the majority of patients.” (AAEP website)
The reason these deadly five diseases are listed as core vaccines is because they pose a possible public health risk, are highly virulent or infectious, have a high mortality rate and can be effectively controlled with routine vaccination with great efficacy. It’s important to remember that vaccines are not 100% effective for every disease but well worth that risk when it comes to protect against these five deadly diseases.
There are many other diseases that horses may or may not need to be protected against with vaccinations. These diseases are listed under “risk based” immunizations depending on travel, environment, geographic circumstances and even competition/racing venue requirements before entering into an event. With recent localized outbreaks of equine herpes virus at race tracks, shows and barrel races, many venues and race tracks require very recent vaccinations for these viruses before permitted onto the grounds. Here is a list of risked based diseases vaccinations are available for: Anthrax, botulism, equine herpes virus 1 & 4, equine viral arteritis, influenza, rotaviral diarrhea and strangles. These diseases and the risk of contracting them must be weighed on an individual horse bases versus the risk of the vaccine itself.
Many vaccines today that are available for horses have all core vaccines in one shot except rabies. One vaccine provider has developed the first all five core diseases in one single vaccine. Horses just like other species require multiple boosters to generate an appropriate immune response to be protective. Unvaccinated horses or horses that don’t have a documented vaccine history it is recommended to have at least one booster four to six weeks after the first dose to get an adequate response and then annually after that. In some endemic areas of the country with higher cases of West Nile and other viral encephalomyelitis diseases due to prolonged mosquito vector season it is often recommended to have a booster in the mid-to-late summer to have added protection against these particular viruses.
Below is a breakdown of each disease and its importance for your horse and even yourself to be protected against.
Rabies –
Highly deadly virus that is unsurvivable for any mammal that contracts the disease and begins to show clinical signs, even for humans. As of 2016 only four people have survived rabies infection after showing clinical signs, so the odds are very poor. One of the most difficult aspects of rabies in horses is the variability of clinical signs. Horses can display two clinical manifestations of the disease: Furious/Mad form or Dumb/Stuporous but really it can look like anything early on. Veterinarians are trained that rabies can display almost as anything and should always be on the list for a horse that presents with neurologic symptoms, especially horses with no vaccine history for rabies. Horses can display colic, ataxia, blindness, hypersalivation, depression, weakness and even lameness. Also there is no ante-mortem test meaning there is no test to confirm rabies until the horse is dead or euthanized and the brain is collected for testing. Rabies is transmitted via bites from infected rabid wildlife such as skunks (highest transmitter in Oklahoma), raccoons, fox and bats.
EEE/WEE –
Eastern and Western equine encephalomyelitis is transmitted like other viral enchephalitides via the mosquito vector. Clinical signs are neurologic signs of ataxia, blindness, head pressing or head tilt, recumbency, seizures and paralysis of the throat/tongue. Only up to 15% of horses survive EEE. WEE has a better survival rate up to 50% and has very similar sign as EEE. Birds are common carriers of EEE/WEE and are the reservoir for these viruses.
West Nile –
A very commonly know virus that is also transmitted by mosquitoes to horses, humans, birds and other mammals. Birds again are the largest reservoir for this virus. The virus affects the central nervous system by creating inflammation around the brain and spinal cord. Symptoms or clinical signs are fever, depression, muscle fasciculations, weakness and ataxia. The severity of the disease is horse dependent and not all horses get the disease but among those horses that do about 1/3 will die from it. Also almost half of horses will have lasting neurologic effects from the disease.
Tetanus –
The causative bacterium was first discovered in 1884 by injecting wound exudates from humans with tetanus into animals leading to the discovery that Clostridium tetani is the causative bacteria. The bacteria is found everywhere in the environment including the soil and manure of horses. Horses are rather sensitive to the neurotoxin produced from Clostridium tetani that leads to the clinical signs of tetanus. The bacteria enter the horse’s body through wounds, cuts or even surgical wounds such as castration sites. The spores of the bacteria turn into the vegetative form when it begins to grow and replicate. The neurotoxin produced from the bacteria enters the central nervous system by peripheral nerves. The clinical signs of tetanus are muscle spasms, stiffness, prolapsed third eyelids, extended head and neck, elevated tail and retracted lips. As the disease progresses, horses will become recumbent and have difficulty breathing. Life saving treatments can be implemented to save the infected horses but still up to 75% of horses will die.
What all these disease have in common besides death is that these deaths are extremely excruciating, painful and miserable. There is no doubt from seeing these cases personally and from watching teaching videos that these horses are suffering enormously. What makes it even more difficult and disheartening when we see these cases is that they are so easily preventable with vaccination. The bottom line is that vaccines can save your horse’s life from these deadly diseases and vaccines are rather inexpensive especially compared to the expensive of trying to treat the horse once they are ill. Please talk to your veterinarian about getting your horse or horses protected with core vaccinations and if any other vaccinations are necessary based on your situation.
Read more great articles in the March 2020 issue of Oklahoma Farm & Ranch.
Equine
Horse Pasture ManagementBy OKFR Staff

As spring weather arrives, horse owners are often eager to turn their horses out to graze and exercise—but is the pasture truly ready?
With proper management, pastures can serve as a high-quality forage source and a safe space for exercise. Effective management can even extend the forage production season, helping to reduce hay expenses. On the other hand, unmanaged pastures often develop weed problems, lack nutritional value, and can pose health risks for horses.
Here are five key steps to help improve and maintain horse pastures:
1. Soil Testing, Fertilizing, and Liming
Annual soil testing is ideal, but due to cost, testing every five years for grazing pastures and every three years for hay fields is a reasonable alternative. Grazing pastures tend to lose nutrients more slowly than hay fields because some nutrients are returned to the soil through horse waste, whereas nutrients in harvested hay are removed entirely.
For guidance on soil testing, fertilization, and liming, producers can refer to the Oklahoma Forage and Pasture Fertility Guide, available through Oklahoma Cooperative Extension and OSU’s Division of Agricultural Sciences and Natural Resources.
2. Over-Seeding and Renovating Bare Spots
Over-seeding helps replenish forage stands and prevent weed invasion. Use a high-quality pasture seed mix, limiting legume content to no more than 25 percent to avoid excessive salivation in horses.
3. Sacrifice Area
Creating a sacrifice area—a small, fenced section (approximately 300 square feet per horse)—gives overgrazed pastures time to recover during periods of heavy grazing or adverse weather. Horses kept in sacrifice areas should always have access to clean water, adequate hay, good drainage, and waste management.
4. Rotational Grazing
Horses are more selective grazers than cattle and will often overgraze their preferred plants, eventually killing them. This leads to spot grazing and pasture degradation. Rotational grazing allows plants time to regrow and helps reduce waste due to trampling.
Manure concentration in preferred areas also decreases grazing efficiency and nutrient distribution, making rotation an essential tool. Horses should be moved to a new pasture when forage is grazed down to 3–4 inches in height.
5. Weed Control
Chemical herbicides are commonly used to manage weeds, but identifying the specific weeds present is essential for selecting the right treatment. To prevent herbicide resistance, avoid long-term use of the same active ingredient and consider complementary methods such as mowing.
Maintaining healthy pasture also includes proper fertilization and rotational grazing, which both help minimize weed invasion.
Forage Selection and Toxic Plant Awareness
Selecting the right forage species depends on factors like land resources, management goals, and available capital. A mix of cool- and warm-season forages generally provides the most cost-effective year-round grazing.
Warm-season grasses, such as Bermuda grass, are commonly used for their high yield, good nutritional value, durability, and responsiveness to nitrogen fertilization. Alternatives include old world bluestem and crabgrass.
Alfalfa, a warm-season perennial legume, is widely used as hay in Oklahoma and can be grazed, though grazing may not always be economical.
Cool-season grasses such as wheat, rye, oats, barley, and ryegrass can be sod-seeded into dormant warm-season pastures to extend the grazing season. Combining ryegrass with small grains often allows grazing later into the spring. Cool-season clovers like red, white, and rose clover also thrive in Oklahoma and provide excellent nutrition.
However, it’s important to recognize and remove potentially toxic plants from horse pastures. These include bitterweed, black locust, cocklebur, horsetail, milkweed, ornamental yew, pigweed, snakeroot, St. John’s wort, wild parsley or carrot, and yarrow. Grasses in the Sorghum genus can contain prussic acid, which may cause severe health issues and even death. Clovers and small grains in humid conditions may also develop mold, which can be dangerous to horses.
Equine
No Foot, No Horse

By Dr. Garrett Metcalf, DVM
There is a wise old saying no foot no horse and that is absolutely true. Horses of all breed, discipline and size must have good healthy feet or they will suffer poor performance, chronic pain or worse succumb to diseases of the foot. There are several medical conditions that require surgical treatment within the hoof wall of the horse and this article will highlight the most common conditions that require surgical treatment and specialty farrier care.
Foot Abscesses –
Foot abscesses are a very common issue that nearly every horse may experience at some point in their lifetime. Abscesses are often minor issues that can be easily corrected by a farrier or veterinarian getting access to the abscess to allow drainage but they can be rather debilitating and sometimes rather serious. Abscesses in general are localized pockets of infection that found its way into the sole or white line of the foot. These abscesses often form because there is some structural abnormality of the foot, trauma that led to bleeding under the sole or improper hoof care that has led to abnormal forces being applied to the foot and of course the old hot nail. For example trimming of the foot without relieving enough sole pressure can lead to overloading the sole and in turn sole bruising setting up for an abscess. Other common abnormalities of the foot that leads to abscessation are laminitis and club feet. These two conditions can cause tearing and stretching of the white line and allow bacteria plus moisture to enter deeper into the foot which in some cases can further destabilize an already unhealthy foot, leading to a life threatening situation. Deep abscess that go untreated for days or weeks can continue to invade and dissect through tissue planes leading to larger abscesses. These large abscess sometimes require surgical intervention to keep them from spreading and to eliminate the abscess all together.
Pedal Bone Osteitis
Pedal bone or the coffin bone is a very unique bone compared to others in the horse. The coffin bone is a rather porous bone that has intimate attachment to the foot capsule and sole. The bone and the hoof tissue has a very high amount of blood supply rightly so because of the vast amount of metabolic rate energy it uses to keep the foot supplied with nutrients. Whenever the hoof is diseased or compromised from laminitis or infection the blood supply can be compromised as well spelling disaster. The disaster that can ensue from these conditions is an infected portion of the coffin bone or sequestration of bone. Bone sequestrums are when bone lacks blood supply and is also infected by bacteria that thrive off of dead tissue. Bone sequestrums are generally rather treatable conditions because once removed the bone can heal but the coffin bone is not the same as other bones in the horse. The coffin bone lacks an outer soft tissue coating called periosteum. Periosteum is a very robust membrane outside of almost all bones that provide blood supply and support healing with progenitor cells and stem cells. The uniqueness of the coffin bone without this important layer leads to poor healing, a more delicate blood supply and makes is more prone to infectious insults.
Treatment of an infected piece of the coffin bone requires aggressive steps in order to prevent spread and destruction of the rest of the coffin bone. Further spread into the coffin bone can lead to further damage to the blood supply to the bone and hoof as well as weakening the bone to the point of fracture under the weight of the horse. Aggressive surgical debridement or removal of infected tissue and bone is the first required step to reduce the amount of infection present in the foot. Secondly is aggressive antibiotic therapy using local delivery methods and systemic routes of administration. Local antibiotic delivery is by means of antibiotic beads, pastes or ointments and by means of regional limb perfusions. Regional limb perfusions are 20-30 minute treatments where antibiotics are delivered to the affected limb via blood vessels in that limb. The antibiotic is held in the limb by a tourniquet above the application site to allow higher concentration of the drug to enter the target tissue or region of the limb. Lastly is proper support of the remaining hoof while still maintaining access to the infected areas to allow local treatment. This step cannot be overlooked and requires the work of a talented farrier to make it possible.
Quittor
Quittor is a chronic deep infection within one of the collateral cartilages of the coffin bone. The collateral cartilages are attached on both wings of the coffin bone and are often referred to on x-ray films as side bone. Lacerations, puncture wounds, trauma and abscesses of the foot can lead to infection of the collateral cartilage. To most people quittor doesn’t sound like a big deal and seems like it would be easily addressed with a few days of antibiotics but that is not the case. This infection deep in the foot can be like a smoldering fire that cannot be put out until the infected cartilage is removed. The diagnosis is usually straight forward because there is often a draining tract with swelling, heat and proud flesh centered over one of the collateral cartilages. The difficulty lies in finding and removing all of the infected tissue not to mention that you have to go through the hoof wall to get there. A hoof wall resection or a window cut in the side of the foot is often needed to access the infected tissue, allow drainage and local treatment at the same time. Quittor can be rather difficult and sometimes require multiple surgeries in order to get the infection cleared up. After the hoof wall resection is made often a specialized shoe will be needed to help protect and keep the foot stable until the hoof grows out the defect in the hoof wall.
Keratoma
Keratoma is a benign tumor like growth that arises from the hoof wall or laminar tissue of the foot called keratin. Keratin is what makes up our hair and nails. This growth continues to expand between the foot wall and the coffin bone leading to pressure necrosis and damage to the coffin bone. This abnormal keratin tissue is usually located at the toe region of the foot and is thought to be triggered by trauma to the hoof tissue. The most common signs of a keratoma are reoccurring foot abscesses in the same location and same foot, plus lameness that are localized to the foot. X-ray, CT and MRI can be used to diagnose keratoma formation within the foot. Often the keratoma is well formed enough to be seen with x-ray but sometimes advance imaging is necessary to make the diagnosis.
The only treatment and cure for a keratoma is surgical removal through the hoof wall. This requires a hoof wall resection with either an oscillating saw or drill bit to removal the hoof wall without damaging the coffin bone. A keratoma has an often distinct appearance by this off white crumbly type tissue that is often easily removed from the surrounding healthy hoof wall. After surgical removal a specialized shoe is needed to protect the foot and allow access to treatment of the surgical site to prevent infection.
Coffin Bone Fractures –
There are many different patterns or ways that a coffin bone can be fracture and some are more serious than others. To keep it simpler we break them down into articular or non-articular meaning do they enter the coffin joint or do they not. Non-articular coffin joint fractures generally are much less serious and can be healed without major surgery. Often times non-articular fractures are stabilized with a special shoe and casting tape placed around the foot to make the hoof itself the “splint” for the coffin bone nestled inside the hoof wall.
Articular fractures of the coffin bone are a much more serious problem because of the damage that is done to the coffin joint. A fracture into any joint is a serious threat to the health of the joint and requires surgical reconstruction as soon as possible to keep the joint from developing crippling arthritis. The trouble again with any surgery on the foot is that the bone is inside the foot making it difficult to access. There are techniques to place screws into the coffin bone through small hoof wall resections to allow stabilization of coffin bone fractures. It does require the right fracture pattern and location to make this surgical treatment a plausible option.
Street Nail
A street nail surgery is used to treatment of deep penetrating injuries that occur at the frog or sole that leads to infection of the bottom of the coffin bone, navicular bone and closely related surrounding soft tissue structures. Street nail procedures are often needed when a metal object such as a nail or screw penetrates and infects the one of the vital structures of the bottom of the foot. This window allows flushing of the synovial structures and removal of damaged/infected tissue. This procedure success is greatly improved with the use of an arthroscopic camera placed in the navicular bursa or coffin joint depending on what area the puncture wound involves. The arthroscope allows better visualization and more thorough flushing of debris and infection out of these tight spaces. Again this surgery cannot be successful with the application of a special shoed called a hospital treatment plate shoe that allows access to the bottom of the foot while keeping the foot clean and protected.
As you can see there is a pretty clear pattern to these hoof conditions: infection and the need for specialized farrier care. In order to be successful in treating these conditions the veterinary surgeon and farrier must work hand in hand to provide the best care for the horse. Although performing surgery on the foot of a horse is challenging and sometimes limited, it is often possible to have successful outcomes with a variety of different conditions.
Equine
Grain Overload in Horses
By Dr. Devon England
You come home after a long day at work, and your feed room door is wide open and grain bins are empty. What do you do? Before you call your vet, figure out what grains were eaten, try to estimate how much and determine which horse or horses got into the feed. Did your horse just get into some hay or alfalfa pellets, or did he get into a high sugar grain like Omolene 300? Did your horse get into chicken or cattle feed? If he did, is it a medicated feed, containing an ionophore like monensin or lasalocid?
Grain overload is an emergency, with better outcomes, the sooner the horse is treated. So, call your veterinarian as soon as you figure out a possible grain overload has occurred. Based on what feed and how much feed your horse consumed, your veterinarian can try to determine the risks to your horse and come up with a treatment plan. Signs of grain overload include colic, lethargy, inappetence, diarrhea and lameness. These signs will vary depending on how long ago grain ingestion occurred and the severity of grain overload.
If your horse got into hay or alfalfa pellets, these are low in sugar and therefore not a high risk for problems. Your horse may just have a mild belly ache (colic) episode. If your horse got into a feed like Omolene 300, they are at risk for grain overload. How severely they are affected will depend on a few factors including how much grain was eaten (5lb vs 30lb), if the horse normally receives that grain or doesn’t receive any grain, and the size of the horse vs the amount of grain eaten. Eating 5lb of grain for a full-size horse who normally receives grain may not be a problem, but that same amount of grain eaten by a small pony who normally only receives hay will be a problem.
Treatment for grain overload should be initiated as soon as possible. This includes lavaging the stomach to remove any remaining grain. Stomach lavage is only successful in removing feed within the first couple of hours. Horses will be given mineral oil or charcoal to decrease absorption of breakdown products (acids) from grain fermentation and protect the intestinal lining from damage. Intravenous fluids are given, because horses can quickly become dehydrated with grain overload, due to digestion products from the grain drawing in a lot of water into the colon. Anti-inflammatories, lidocaine, and ice boots are used in more severe cases to decrease the risk of laminitis. In more severe cases with damage of the intestinal lining, antibiotics may be used to prevent infections associated with bacterial escape from the damaged intestine.
If your horse got into medicated feed containing an ionophore, your horse is at high risk for heart failure and muscle damage, on top of grain overload. Ionophores are toxic at very low doses in horses (2mg/kg). These drugs are added to livestock feed to decrease parasites (coccidia), to help with feed efficiency, to decrease risk of bloat and to decrease methane emissions. If your horse has eaten ANY amount of medicated feed, they should be immediately seen by your veterinarian, even if they are not showing any clinical signs. Horses can have no clinical signs or be mildly lethargic in cases where small amounts of medicated feed were eaten but still have evidence on blood work or muscle and heart damage. Clinical signs include initial inappetence or colic signs, weakness or neurologic signs in the hind end, muscle fasciculations (twitching), laying down more, and not being able to stand. There is no anti-dote to ionophore toxicity. Treatment may include mineral oil, IV fluids, anti-inflammatories and supportive care, depending on how soon toxicity is identified. In severe cases, horses can die or develop heart failure, necessitating euthanasia. In less severe cases, especially if identified and treated early, horses can recover fully.
Grain overload can come with serious complications if severe or medicated feeds are involved, especially if treatment is delayed. Secure your feed room as best as possible and keep medicated livestock feeds in a separate location to prevent cross-contamination. And if you have any concerns about your horse getting into feed, call your veterinarian as soon as possible.
This article was originally published in the February 2025 issue of Oklahoma Farm & Ranch.
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